Ohtani et al., Purinergic Signal 2008
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Evidence for the possible involvement of the P2Y(6) receptor in Ca ( 2+ ) mobilization and insulin secretion in mouse pancreatic islets
Balasubramanian et al., Biochem Pharmacol 2010
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Overall, the results demonstrate that selective stimulation of P2Y(1) and P2Y(6) receptors increases insulin secretion that accompanies intracellular calcium release, suggesting potential application of P2Y receptor ligands in the treatment of diabetes