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CAT — NFKB1

Text-mined interactions from Literome

Wang et al., Ann Clin Lab Sci 1999 : Superoxide dismutase ( SOD ), but not catalase or sodium formate, inhibited this NF-kappaB activation, suggesting that O2*- rather than H2O2 or *OH, radicals play the most critical role in this induction
Ye et al., Ann Clin Lab Sci 2000 : Exogenous superoxide dismutase ( SOD ) enhanced the NF-kappaB activation by PMA, while catalase blocked it
Ghassemi et al., AIDS Res Hum Retroviruses 2000 : In addition, transient transfection of U937 cells with full-length wild-type as well as NF-kappaB binding site deleted mutant HIV-1 LTR-CAT constructs revealed that MAC induced HIV-LTR CAT is NF-kappaB dependent
Kang et al., J Toxicol Environ Health 2000 : Further evidence for the involvement of ROS in NF-kappaB activation is that 1 mM H2O2 enhanced NF-kappaB/DNA binding and that this activation was inhibited by catalase
Jaspers et al., Am J Respir Cell Mol Biol 2000 (MAP Kinase Signaling System) : Both nuclear translocation of NF-kappaB and enhanced kappaB dependent transcription induced by V ( IV ) were inhibited by overexpression of catalase , but not Cu, Zn superoxide dismutase ( Cu, Zn-SOD ), indicating that peroxides rather than superoxides initiated signaling
Murley et al., Free Radic Biol Med 2001 : Neither catalase nor pyruvate when added to the culture medium to minimize hydrogen peroxide production had an effect on NFkappaB activation by SH
Weber et al., Chem Res Toxicol 2001 : Catalase fully inhibited peak TGHQ mediated TRE- and NF-kappaB binding activity
Kitaura et al., FEMS Immunol Med Microbiol 2001 (HIV Infections...) : These findings indicated that activation of Mycobacterium induced LTR CAT is NF-kappaB dependent
Fan et al., J Biol Chem 2003 (Anoxia) : Overexpression of glutathione peroxidase-1 or catalase , but not Mn-SOD or Cu, Zn-SOD, significantly reduced both NF kappa B activation and tyrosine phosphorylation of I kappa B alpha
Kontou et al., Biol Chem 2003 (Chromosomal Instability...) : Cotransfection of the NF-kappaB dependent CAT plasmid with the Trx/nuc-plasmid into FA fibroblasts increased the CAT expression to almost that of control cells, indicating that in this model system with diminished thioredoxin content NF-kappaB requires thioredoxin for binding to its specific promotor
Jang et al., Biochem Biophys Res Commun 2004 : Catalase also induced activation of NF-kappaB , PI3K, ERKs, p38s, or JNKs. Catalase induced COX-2 expression was abrogated by treatment of MG-132 ( a NF-kappaB inhibitor ) or LY294002 ( a PI3K inhibitor ), but not by treatment of PD98059 ( an ERK inhibitor ), SB203580 ( a p38 inhibitor ), or SP600125 ( a JNK inhibitor )
Pawate et al., J Neurosci Res 2004 (Encephalitis...) : Phox inhibitors and catalase also suppressed LPS/IFNgamma induced expression of cytokines, i.e., interleukin (IL)-1, IL-6, and tumor necrosis factor (TNF)alpha and blocked LPS activation of MAP kinases ( i.e., p38 MAPK, c-Jun N-terminal kinase and extracellular signal regulated kinase ), NFkappaB , and IFNgamma induced STAT1 phosphorylation
Jang et al., Biochem Pharmacol 2004 : Catalase induces the expression of inducible nitric oxide synthase through activation of NF-kappaB and PI3K signaling pathway in Raw 264.7 cells
Jang et al., Cell Signal 2005 : Interestingly, there was PI3K dependent activation of AKT, p70S6K, JNKs, and NF-kappaB in response to catalase
Lee et al., J Cell Physiol 2008 : Catalase inhibited the effect of H2O2 on MAPKs and NF-kappaB
Shan et al., J Biomed Biotechnol 2009 (Brain Injuries...) : Interestingly, we found, PSPC decreased the expression level of glial fibrillary acidic protein (GFAP), inducible nitric oxide synthase (iNOS), and cyclooxygenase-2 (COX-2), inhibited nuclear translocation of nuclear factor-kappaB (NF-kappaB) , increased the activity of copper/zinc superoxide dismutase ( Cu/Zn-SOD ) and catalase (CAT) , and reduced the content of malondialdehyde ( MDA ), respectively
Libermann et al., Mol Cell Biol 1990 : However, stimulation of U-937 and HeLa cells by inducers of NF-kappa B led to a dramatic increase in CAT activity
Das et al., Am J Physiol 1995 : SOD and catalase ( 500 U/ml ) plus ethanol ( 1 mM ) did not inhibit activation of NF-kappa B or elevation of steady-state MnSOD mRNA levels by NAC, DTT, or 2-ME
Yao et al., Environ Health Perspect 1995 : Linker scanning mutational analysis of transcription factor binding sites in the promoter revealed that both the NF kappa B and an adjacent aromatic hydrocarbon response element ( AhRE ) are required for TCDD dependent CAT expression
Suzuki et al., Biochem Biophys Res Commun 1995 : Transient overexpression of catalase does not inhibit TNF- or PMA induced NF-kappa B activation ... Overexpression of catalase , however, did not block TNF- or PMA induced NF-kappa B activation
Ginn-Pease et al., Biochem Biophys Res Commun 1996 : However, signals induced by oxidative conditions effectively cooperated with stimulatory signals provided by PMA but not with T cell receptor/CD3 stimulation to induce significant increases in NF kappa B CAT responses
Schmidt et al., Chem Biol 1995 (Second Messenger Systems) : The catalase inhibitor aminotriazol restored NF-kappa B induction
Chen et al., Ann Clin Lab Sci 1998 : Catalase , metal chelator, deferoxamine, and the silanol group ( SiOH ) blocker, poly ( 2-vinylpyridine-N-oxide ) ( PVPNO ), also inhibited silica induced NF-kappa B activation
Natarajan et al., Arch Biochem Biophys 1998 : The NF-kappaB dependent CAT reporter gene expression in transient transfection assays was also suppressed by the PTK inhibitors
Lentsch et al., Am J Pathol 1998 (Alveolitis, Extrinsic Allergic...) : N-acetylcysteine, but not catalase , suppressed activation of lung NF-kappaB
Nilakantan et al., Carcinogenesis 1998 : Liver-specific catalase expression in transgenic mice inhibits NF-kappaB activation and DNA synthesis induced by the peroxisome proliferator ciprofibrate ... Ciprofibrate increased the activation of nuclear factor (NF)-kappaB in non-transgenic mice, but this increase was inhibited by catalase overexpression
Chen et al., Biochem Pharmacol 1998 : The increase in expression of mRNA for COX-2 induced by catalase may be related to the ability of catalase to stimulate cyclic AMP response element ( CRE ) and NF-IL6 transcription factors, but not nuclear factor kappa B (NF-kappaB) , for electrophoretic mobility shift assays ( EMSA ) showed that catalase enhanced nuclear factor binding to cyclic AMP response element and NF-IL6 but not to NF-kappaB
Vollebregt et al., FEBS Lett 1998 : The neutrophil NADPH oxidase inhibitor diphenylene iodonium, catalase , and other oxidant scavengers did not inhibit NF-kappaB activation, and no activation was seen with added hydrogen peroxide