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MAP3K2 — NFKB1

Text-mined interactions from Literome

Zhao et al., J Biol Chem 1999 : We now show that MEKK2 and MEKK3 can in vivo activate IKK-alpha and IKK-beta, induce site-specific IkappaBalpha phosphorylation, and, relatively modestly, activate an NF-kappaB reporter gene ... In addition, dominant negative versions of either IKK-alpha or IKK-beta abolish NF-kappaB activation induced by MEKK2 or MEKK3, thereby providing evidence that these IKKs mediate the NF-kappaB inducing activities of these MEKKs
Neumann et al., Biol Chem 2006 : Furthermore, we show that mitogen activated protein kinase kinase kinases ( MAP3K ), like TPL2 ( tumour progression locus 2 ) and transforming growth factor beta activated kinase 1 ( TAK1 ), have no impact on H. pylori induced activation of NF-kappaB
Gohda et al., Biochem Biophys Res Commun 2007 : These results strongly suggest that unlike cytokine signaling, Tax induced NFkappaB activation does not involve K63 polyubiquitination mediated MAP3K activation