Gene interactions and pathways from curated databases and text-mining

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LIF — NFYA

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: NFYA → LIF (increases, LIF Activity, NFYA Activity) Curtis et al., Leukemia 2001*
    Evidence: Previously, we have shown that interleukin-6 (IL-6) or leukemia inhibitory factor (LIF)-induced differentiation of the myeloid cell line M1 was associated with a rapid increase in the level of mRNA encoding the signaling adaptor protein, SKAP55R These results suggest NF-Y binding may be a common mechanism of IL-6/LIF-regulated transcription in myeloid cells.