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E2F1 — TNF
Text-mined interactions from Literome
Carlberg et al., Int J Oncol 1999
:
Protein binding assays indicate that
TNF and gamma-INF did not effect the ability of the ME1a2 factor to bind to its site but did significantly
repress E2F factor binding to its DNA sequence
Kishore et al., Circ Res 2003
:
Tumor necrosis factor mediated
E2F1 suppression in endothelial cells : differential requirement of c-Jun N-terminal kinase and p38 mitogen activated protein kinase signal transduction pathways ... Taken together, these data suggest a differential requirement of JNK1 and p38 MAPK in
TNF regulation of
E2F1
Tammali et al., Endocrinology 2010
(Diabetes Mellitus, Experimental) :
Treatment of VSMC with AR inhibitor sorbinil prevented HG- as well as
TNF-alpha induced phosphorylation of retinoblastoma protein and activation of
E2F-1