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CORT — VIP
Text-mined interactions from Literome
Alexander et al., Neuropeptides 1995
:
The relative roles of hypothalamic corticotropin-releasing-hormone (CRH) and vasopressin ( AVP ) as mediators of the stimulant
effect of
vasoactive intestinal peptide (VIP) and peptide histidine isoleucine (PHI) on ACTH and
corticosterone (CORT) secretion, were examined using receptor blockade of endogenous CRH and AVP ... ACTH and
CORT stimulation by
VIP were inhibited 78 and 72 %, respectively, by pretreatment with the CRF antagonist, 59 and 57 %, respectively, by pretreatment with the AVP antagonist and about 78 % by combined pretreatment with the CRF and AVP antagonists
Alexander et al., Regul Pept 1995
:
Individual studies involving the PVN administration of either VIP or PHI in doses ranging from 0.3 to 30.0 nmol/rat demonstrated that
VIP increases both ACTH and
CORT secretion throughout the administered range