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EPHB2 — SP3

Text-mined interactions from Literome

Strowski et al., FASEB J 2004 (Helicobacter Infections...) : Helicobacter pylori stimulates host vascular endothelial growth factor-A ( vegf-A ) gene expression via MEK/ERK dependent activation of Sp1 and Sp3
Jiang et al., Mol Cell Endocrinol 2012 (MAP Kinase Signaling System) : Phorbol esters enhance 1a,25-dihydroxyvitamin D3-regulated 25-hydroxyvitamin D-24-hydroxylase ( CYP24A1 ) gene expression through ERK mediated phosphorylation of specific protein 3 (Sp3) in Caco-2 cells
García-Ruiz et al., Endocrinology 2012 (Fibrosis) : In conclusion, in HSCs, leptin up-regulates Col1a(I) gene expression after activating NADPH oxidase, inducing oxidative stress, aldehyde-protein adduct formation, and ERK1/2 phosphorylation, which in turn activates Sp1/Sp3 and provokes the binding of these two factors to regulatory elements located between -161 and -110 bp of the Col1a(I) promoter