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MAX — TP53
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Kirch et al., Oncogene 1999
:
Expression of human
p53 requires synergistic activation of transcription from the p53 promoter by AP-1, NF-kappaB and
Myc/Max
Yang et al., Hepatology 2009
(Cholestasis...) :
Switch from Mnt-Max to
Myc-Max induces
p53 and cyclin D1 expression and apoptosis during cholestasis in mouse and human hepatocytes ... The current work tested the hypothesis that the switch from Mnt-Max to
Myc-Max is
responsible for
p53 and cyclin D1 up-regulation and apoptosis during cholestasis