Liu et al., Cancer Res 2003
(Lung Neoplasms...) :
In this study, we test the possibility that HDAC inhibitor may increase RECK expression to inhibit MMP activation and cancer cell invasion
Wang et al., J Cereb Blood Flow Metab 2011
(Brain Edema...) :
Our findings suggest that BBB protection by VPA involves HDAC inhibition mediated suppression of NF-?B activation, MMP-9 induction, and tight junction degradation
Saito et al., Osteoarthritis Cartilage 2013
(MAP Kinase Signaling System) :
HDAC inhibitors ( TSA : 10nM, MS-275 : 100nM ) suppressed CTS induced expression of RUNX-2, ADAMTS-5, and MMP-3 at both the mRNA and protein levels within 1h