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Chen et al., Life Sci 1999 : The activity of NF-kappaB induced by TNF-alpha was blocked by calpain inhibitor I, a potent NF-kappaB inhibitor
Ruetten et al., Mediators Inflamm 1999 : The upregulation of ICAM-1 expression on J774.2 macrophages caused by LPS was significantly inhibited by pretreatment of the cells with inhibitors of the activation of the nuclear transcription factor NF-kappaB , such as L-1-tosylamido-2-phenylethylchloromethyl ketone ( TPCK ), pyrrolidine dithiocarbamate ( PDTC ), rotenone or calpain inhibitor I, but not by the tyrosine kinase inhibitors, tyrphostin AG126 or genistein
Kim et al., J Immunol 2000 : Sulfasalazine and calpain inhibitor I, inhibitors of NF-kappaB activation, blocked HRV-16 induced formation of NF-kappaB complexes with oligonucleotides from both cytokines, but did not inhibit mRNA induction for either cytokine
Kouba et al., J Biol Chem 2001 : To explore alternative signaling mechanisms in dermal fibroblasts, we found that the intracellular calcium chelator, 3,4,5-trimethoxybenzoic acid, and the calpain inhibitor , N-acetyl-Leu-Leu-norleucinal, both blocked NF-kappa B activation ; however, the specific proteosome inhibitor, lactacystin, failed to do so