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ABCA1 — SREBF2
Text-mined interactions from Literome
Plat et al., FASEB J 2002
:
Consequently, increased plant stanol levels within the enterocyte activate cholesterol efflux through
ABCA1- but not
SREBP-2 mediated endogenous cholesterol synthesis even if intracellular cholesterol concentrations are lowered through consumption of plant stanols
Zeng et al., J Biol Chem 2004
:
We investigated the
regulation of
ABCA1 by
SREBP2 in vascular endothelial cells ( ECs )
Wong et al., Biochem J 2006
:
However, it was subsequently reported that
ABCA1 expression is
down-regulated by
SREBP-2 through binding of SREBP-2 to an E-box element in ABCA1 's proximal promoter ... In the present study, we employed a set of CHO ( Chinese-hamster ovary ) mutant cell lines to investigate the
role of
SREBP-2 in the regulation of
ABCA1