Gene interactions and pathways from curated databases and text-mining

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CSF3 — JAK3

Text-mined interactions from Literome

Koay et al., Cell Signal 2002 (MAP Kinase Signaling System) : The G-CSFR membrane proximal region containing the Box 2 homology sequence was determined to be critical for proliferative signaling, as well as for activation of Janus kinase ( JAK2 ) and p44/42 mitogen activated protein kinase ( MAPK ) following G-CSF stimulation
Wang et al., Oncogene 2002 : Antisense inhibition of c-Cbl expression in DT40GR cells led to enhanced Jak-STAT activation following G-CSF stimulation
Mangan et al., Oncogene 2006 : Granulocyte colony stimulating factor induced upregulation of Jak3 transcription during granulocytic differentiation is mediated by the cooperative action of Sp1 and Stat3 ... To gain insight into the regulation of G-CSF induced transcription of Jak3 , we constructed deletion and linker scanning mutants of the Jak3 promoter sequences and performed luciferase reporter assays in the murine myeloid cell line 32Dcl3, with and without G-CSF stimulation
Shih et al., PloS one 2012 : Furthermore, aciculatin significantly inhibited the G-CSF mediated phosphorylation of Janus kinase-signal transducer and activator of transcription ( JAK-STAT ) and Akt and neutrophil differentiation from precursor cells