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ANXA1 — FPR2
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
ANXA1
→
FPR2
(direct_complex)
Ye et al., Biochem Biophys Res Commun 1992*
-
Reactome Reaction:
ANXA1
→
FPR2
(reaction)
Rubio et al., Genomics 1999, Ye et al., Biochem Biophys Res Commun 1992*, Dowal et al., J Biol Chem 2006, Lambert et al., Science signaling 2008, Amatruda et al., Proc Natl Acad Sci U S A 1991, Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Ferguson et al., J Biol Chem 1986, Takami et al., Brain Res Mol Brain Res 1994, Chen et al., Biochim Biophys Acta 1996
Text-mined interactions from Literome
Walther et al., Mol Cell 2000
(Calcium Signaling) :
A novel ligand of the
formyl peptide receptor :
annexin I regulates neutrophil extravasation by interacting with the FPR
Babbin et al., J Immunol 2008
(Colitis...) :
Additionally, differential expression of ALX/FPLR-1 in control and DSS treated WT and AnxA1-deficient animals suggested a potential
role for
AnxA1 in regulating
ALX/FPRL-1 expression under pathophysiological conditions
Bena et al., J Biol Chem 2012
:
In desensitization experiments, the N-terminal region was dispensable for
AnxA1 induced
FPR2/ALX down-regulation in both the homologous and heterologous desensitization modes