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OSM — TP53

Text-mined interactions from Literome

Liu et al., Cell Growth Differ 1999 (Breast Neoplasms) : The expression of p53 tumor suppressor gene in breast cancer cells is down-regulated by cytokine oncostatin M
Chipoy et al., Oncogene 2007 (Osteosarcoma) : Pharmacological inhibitors, dominant negative signal transducer and activator of transcriptions ( STATs ), stable RNA interference and knockout cells indicated that the transcription factors p53 and STAT5, which are activated by OSM , are implicated in the sensitization to apoptosis, being responsible for Bax induction and Bcl-2 reduction, respectively