Gene interactions and pathways from curated databases and text-mining

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PDCD4 — PSEN2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

da Costa et al., Curr Alzheimer Res 2005 (Alzheimer Disease) : The aim of this review is to focus on the mechanisms by which presenilin 2 affects the programmed cell death with special emphasis on the role of the proteolytically derived presenilin fragments generated by both presenilinase- and caspases
Janicki et al., J Cell Biol 1997 (Alzheimer Disease) : Although HeLa cells are strongly predisposed to continued mitosis, expression of PS-2 induced programmed cell death ( apoptosis )