Gene interactions and pathways from curated databases and text-mining

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GNRH1 — PGF

Text-mined interactions from Literome

Braileanu et al., Reproduction 2001 : Neither GnRH nor lysine-vasopressin induced phospholipase C activity, increased [ Ca ( 2+ ) ] ( i ) or stimulated PGF ( 2alpha ) production in any endometrial cell type
Naor et al., Mol Endocrinol 2007 (MAP Kinase Signaling System) : PGF ( 2alpha ), but not PGI2 or PGE2, reduced GnRH-induction of LHbeta gene expression, but not the alpha-gonadotropin subunit or the FSHbeta subunit genes
Gobbetti et al., Gen Comp Endocrinol 1991 : These results suggest that R. esculenta interrenals could be a GnRH dependent PGF2 alpha secreting tissue ... This finding, taken together with other previous studies, strongly suggests that the end of the breeding period in R. esculenta depends on GnRH induced PGF2 alpha mediated enhancement of estradiol synthesis in a steroidogenetic organ ( probably interrenals )
Gobbetti et al., Cell Signal 1993 : Mammalian gonadotropin releasing hormone increases PGF2 alpha production activating diacylglycerol lipase in Rana esculenta interrenal
Gobbetti et al., Prostaglandins Other Lipid Mediat 1998 : The aim of this study was to clarify the possible involvement of nitric oxide ( NO ) on prostaglandin ( PG ) E2-9-ketoreductase activity in the gonadotropin releasing hormone (GnRH) dependent PGF2 alpha synthesis by the interrenal gland of the female water frog, Rana esculenta, during the post-reproduction ... GnRH and SNP increased PGF2 alpha production and PGE2-9-ketoreductase activity, and decreased production of PGE2 and GnRH increased NO synthase activity ... This study indicates that NO may be involved in regulation of the R. esculenta post-reproduction through stimulation of PGE2-9-ketoreductase activity in GnRH dependent PGF2 alpha synthesis by the frog interrenal gland