Gene interactions and pathways from curated databases and text-mining

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AGAP2 — CCND1

Text-mined interactions from Literome

Ye et al., Cell 2000 : Dominant negative PIKE prevents the NGF enhancement of PI3K and upregulation of cyclin D1
Chan et al., EMBO J 2010 : Depletion of PIKE-A in HC11 epithelial cells diminished PRL induced STAT5 activation and cyclin D1 expression, resulting in profoundly impaired cell proliferation in vitro