Hellgren et al., Experientia 1979
:
However, in the bioassay system used, the effect of PLS was different from that of PGF2 alpha and PGI2 but similar, although not identical, to that of arachidonic acid and PGE2
Ichikawa et al., Arthritis Rheum 1994
(Antiphospholipid Syndrome) :
All of the monoclonal aCL bound to anionic PLs , only in the presence of beta 2-GPI Gharavi et al., Am J Reprod Immunol 1998
(Antiphospholipid Syndrome) :
These findings suggest that the binding of autoimmune aPL antibodies to beta(2)GPI-PL complex results in abnormally tighter interaction between beta(2)GPI and PLs , which may lead to physiological dysfunction of beta(2)GPI as a regulator of coagulation