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GPI — NPPA
Text-mined interactions from Literome
Oliveira-Souza et al., Kidney Int 2001
:
The
effects of AVP and/or
ANP on
pHi and [Ca2+ ] i were investigated in Madin-Darby canine kidney ( MDCK ) cells by the fluorescent probes BCECF-AM and Fluo 4-AM, respectively
Oliveira-Souza et al., Kidney Int 2002
:
The
effects of Ang II and/or
ANP on the regulation of
pHi via H+-ATPase and of [ Ca2+ ] i was investigated in Madin-Darby canine kidney cells ( MDCK ) by the fluorescent probes BCECF-AM and Fluo-4/AM, respectively
Baldini et al., Cell Physiol Biochem 2005
:
The
ANP effects on
pHi were evaluated by fluorescence spectrometry ... The
ANP effect on
pHi was coupled to an increased p38 MAPK phosphorylation and a down-regulation of mRNA NHE-1 expression and protein levels
Azizi et al., Eur J Endocrinol 1995
:
Next, PGE2, but not PGF2 alpha or
PGI2 ( 10 mumol ),
increased ANP release ... We conclude that : the effect of isoproterenol on ANP release is sensitive to indomethacin and H89 ; PGE2, but not PGE2 alpha or
PGI2 ,
increases ANP release ; isoproterenol promotes myocardial PGE2 formation independently of adenylate cyclase and PKA activation pathways ; and PGE2 induced ANP release is mediated by cAMP production and subsequent PKA activation
Tajima et al., Circulation 1998
(Aortic Valve Stenosis...) :
In the presence of 10 ( -6 ) mol/L
ANP , fractional cell shortening was 78+/-5 % of baseline ( P < 0.05 ) and
pHi was
reduced by 0.16+/-0.04 U from baseline ( P < 0.01 ) without changes in [Ca2+ ] i ... The
effects of
ANP on contractility and
pHi were prevented in the presence of 5- ( N-ethyl-N-isopropyl ) -amiloride ( EIPA ), which inhibits the Na+/H+ exchanger ... In contrast,
ANP causes no effects on contractility and
pHi in hypertrophied myocytes, suggesting a suppression in the coupling of the ANP-cGMP intracellular signaling pathway to the Na+/H+ exchanger