Gene interactions and pathways from curated databases and text-mining

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HOXA9 — TPO

Text-mined interactions from Literome

Kirito et al., Mol Cell Biol 2004 (MAP Kinase Signaling System) : To extend our studies, we investigated the effects of TPO on HOXA9 in this same cell population ... Although overall levels of the transcription factor were not affected, we found that TPO induced the nuclear import of HOXA9 both in UT-7/TPO cells and in primitive Sca-1 ( + ) /c-kit ( + ) /Gr-1 ( - ) hematopoietic cells in a mitogen activated protein kinase dependent fashion
Kaushansky et al., Ann N Y Acad Sci 2005 : We found that TPO enhances the transcription of HoxB4, induces the nuclear localization of HoxA9 , and upregulates VEGF expression by reducing the ubiquination of hypoxia inducible factor