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BCL2 — GLI1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Cayuso et al., Development 2006
:
Analysis of neural cells indicates that
Shh/Gli signaling
regulates the G1 phase of cell cycle and the expression of the anti-apoptotic factor
Bcl2
Hegde et al., Mol Cancer Res 2008
(Leukemia, Lymphocytic, Chronic, B-Cell) :
Furthermore, selective down-regulation of
GLI1 by antisense oligodeoxynucleotides ( GLI1-ASO )
results in decreased
BCL2 expression and cell survival, suggesting that GLI1 may regulate BCL2 and, thereby, modulate cell survival in B-CLL
Mazumdar et al., Cancer Res 2011
(Carcinoma...) :
GANT61 specifically targeted Gli1 and Gli2 substantiated by specific inhibition of ( i ) direct binding of
Gli1 and Gli2 to the promoters of target genes HIP1 and BCL-2, ( ii ) Gli-luciferase activity, and ( iii ) transcriptional
activation of
BCL-2