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EGF — RUNX2
Text-mined interactions from Literome
Pei et al., Acta Pharmacol Sin 2003
(MAP Kinase Signaling System) :
And mitogen activated protein kinase ( MAPK ) inhibitor, PD 98059 ( 10 micromol/L ), completely blocked IGF-1, GM-CSF, and
EGF induced expression of
Cbfa1 promoter activity ( P < 0.01 ) ... IGF-I, GM-CSF, and
EGF could
increase the promoter activity and the mRNA expression of murine
Cbfalpha1 gene in MC3T3-E1 and C2C12 cells
Park et al., Mol Endocrinol 2010
:
The hCG induced
Runx2 expression was
reduced by antiprogestin ( RU486 ) and
EGF-receptor tyrosine kinase inhibitor ( AG1478 ), indicating the involvement of EGF signaling and progesterone mediated pathways