Gene interactions and pathways from curated databases and text-mining

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MAPK1 — PRKCD

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Ishino et al., Mol Carcinog 2002 (Pancreatic Neoplasms) : Overexpression of nPKCdelta or nPKC epsilon activated MAPK and promoted anchorage independent growth
Jackson et al., Mol Endocrinol 2003 (MAP Kinase Signaling System...) : FGF induction of rPRL transcription is independent of Ras, but mediated by a protein kinase C-delta (PKCdelta) dependent activation of MAPK ( ERK )
Melchior et al., Exp Cell Res 2008 : We then demonstrated that CyPB induced cell adhesion and p44/42 MAPK activation were dependent on the participation of phosphoinositide 3-kinase and subsequent activation of protein kinase C-delta
Lomonaco et al., J Biol Chem 2008 : Phosphorylation of protein kinase Cdelta on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1 : role in the apoptotic effect of etoposide