Gene interactions and pathways from curated databases and text-mining

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AMPH — BDNF

Text-mined interactions from Literome

Frey et al., Life Sci 2006 (Disease Models, Animal) : In the second experiment, AMPH decreased BDNF levels and Li and VPT increased BDNF levels in rat hippocampus
Griesbach et al., Neuroscience 2008 (Brain Injuries) : Exercise or AMPH alone significantly increased BDNF protein in sham and CCI rats, but this effect was lost with the combined treatment
Valvassori et al., J Psychopharmacol 2011 (Disease Models, Animal...) : In the hippocampus CBD ( 15 mg/kg ) reversed the d-AMPH induced damage and increased ( 30 mg/kg ) brain derived neurotrophic factor (BDNF) expression ... In conclusion, we could not observe effects on locomotion, but CBD protect against d-AMPH induced oxidative protein damage and increased BDNF levels in the reversal model and these effects vary depending on the brain regions evaluated and doses of CBD administered
MacĂȘdo et al., Bipolar Disord 2012 (Disease Models, Animal) : Furthermore, ALA reversed AMPH induced decreases in BDNF and GSH in the HC