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EPO — GSK3B
Text-mined interactions from Literome
Wu et al., Apoptosis 2007
:
The
effects of
EPO on
GSK-3beta and caspase-3 activities were also blocked by LY294002
Nishihara et al., J Mol Cell Cardiol 2007
(Disease Models, Animal...) :
To get an insight into the mechanism by which phospho-GSK-3beta protects the myocardium from ischemia/reperfusion injury, we examined the
effects of IPC and
EPO on interactions between
GSK-3beta and subunits of the mitochondrial permeability transition pore ( mPTP ) in this study ...
IPC+EPO significantly increased the levels of GSK-3beta and phospho-GSK-3beta that were co-immunoprecipitated with ANT to 145+/-8 % and 143+/-16 %, respectively, of baseline but did not
induce phospho-GSK-3beta-VDAC binding ... A PKC inhibitor and a PI3 kinase inhibitor suppressed the
IPC+EPO induced increase in the level of
phospho-GSK-3beta-ANT complex
Ohori et al., Am J Physiol Heart Circ Physiol 2008
:
However,
EPO increased the level of
Ser9-phospho-GSK-3beta colocalized with mitochondria by 50 % in a phosphatidylinositol 3-kinase dependent manner
Miki et al., Diabetes 2009
(Body Weight...) :
However, neither phosphorylation of Akt and
GSK-3beta nor infarct size limitation was
induced by
EPO in OLETF rats