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GPX4 — NOS1
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Li et al., Brain Res 2002
(Brain Ischemia...) :
Spiramine T ( 1.0 and 2.0 mg kg ( -1 ) i.p. ) markedly reduced the content of lipid peroxide (LPO), increased the
glutathione peroxidase ( GSH-PX ) activity, and
inhibited the increase of
nitric oxidase (NOS) activity and nitric oxide production in the cortex during ischemia-reperfusion in gerbils
Liu et al., Brain Res 2012
(Disease Models, Animal...) :
The results showed that after PFC administration, the latency to first electrical discharge in EEG was significantly shortened ; MDA, H ( 2 ) O ( 2 ), NO levels and
NOS activity
increased ; and SOD,
GPx and CAT activities decreased