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PTK2B — STAT3

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: STAT3 → PTK2B (increases, PTK2B Activity, STAT3 Activity) Shi et al., J Biol Chem 2004*
  Evidence: These results indicate that Pyk2 facilitates EGFR- and c-Src-mediated Stat3 activation, thereby implicating Pyk2 activation as a potential co-mediator in triggering Stat3-induced oncogenesis.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: STAT3 — PTK2B (in vitro) Shi et al., J Biol Chem 2004*
• IRef Intact Interaction: Complex of 70 proteins (association, anti bait coimmunoprecipitation) Thelemann et al., Mol Cell Proteomics 2005