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JUN — VIP
Text-mined interactions from Literome
Wang et al., J Neuroimmunol 2000
:
The
effects of
VIP/PACAP on
c-Jun and JunB expression lead to changes in the composition of the AP-l complexes, from c-Jun/Fos to JunB/Fos dimers, with a subsequent decrease in DNA binding and loss of transactivating activity
Foster et al., J Dent Res 2005
:
In parallel, we showed that
VIP inhibits nuclear translocation of NFkappaB and
c-Jun in a time dependent manner, but does not decrease the expression of CD14 receptors
Son et al., Exp Neurol 2007
(Constriction, Pathologic...) :
Moreover, transcription factor
c-Jun regulates the expressions of both
VIP and NPY in cultured DRG neurons ... To elucidate the role of c-Jun in the induction of neuropathic pain hypersensitivity, we examined whether activated
c-Jun affects pain behavior and the expressions of
VIP and NPY following chronic constriction injury ( CCI ) of rat sciatic nerve ... These results show that the activation of
c-Jun in DRGs
induces VIP and NPY upregulation and contributes to the pathogenesis of neuropathic pain following CCI
Mulderry et al., Eur J Neurosci 1996
:
Regulation of
VIP and other neuropeptides by
c-Jun in sensory neurons : implications for the neuropeptide response to axotomy ... To determine whether
VIP induction is
dependent on transcriptional regulation by
c-Jun , we exploited the fact that c-Jun and VIP are also induced in cultured sensory neurons ...
VIP induction in sensory neurons therefore probably
results from transcriptional activation by
c-Jun acting in combination with other factor ( s ), possibly acting through the CRE