Gene interactions and pathways from curated databases and text-mining

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JUN — PKD3

Text-mined interactions from Literome

Hurd et al., Biochem Biophys Res Commun 2001 : Induced expression of constitutively active, but not kinase dead PKD, suppressed EGF stimulated c-Jun phosphorylation at Ser 63, demonstrating that activated PKD is sufficient to suppress c-Jun phosphorylation
Yamashita et al., Int Immunopharmacol 2010 : We investigated the roles of PKD on FcepsilonRI induced activator protein-1 (AP-1) activation and proinflammatory cytokine productions in mast cells ... The overexpression of PKD enhanced the induction of AP-1 luciferase activity by FcepsilonRI stimulation, while it had no effect on luciferase activities dependent upon NF-kappaB and NF-AT activated by FcepsilonRI stimulation ... Moreover the overexpression of PKD strongly enhanced the phosphorylation of both c-Jun and c-Fos following FcepsilonRI stimulation