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S100A12 — VEGFA
Text-mined interactions from Literome
Yu et al., Regul Pept 2006
(MAP Kinase Signaling System) :
We hypothesized that
CGRP might
regulate the expression of
VEGF by human keratinocytes ... The
CGRP mediated
VEGF induction was also effectively inhibited by a pretreatment with the CGRP receptor antagonist CGRP 8-37 ... These results suggest that
CGRP regulates the expression of
VEGF through the CGRP receptor and ERK1/2 MAPK signaling pathway in human HaCaT keratinocytes
Sun et al., Front Biosci (Elite Ed) 2010
(Disease Models, Animal...) :
Moreover,
CGRP increased the levels of
vascular endothelial growth factor and stimulated angiogenesis
Wang et al., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2011
:
CGRP can promote the migration of BMSCs and
stimulate the protein expression of
VEGF , which may plays an important role in regulating bone metabolism by increasing angiogenesis
Nakashima et al., Biochem Biophys Res Commun 2012
(Osteoarthritis) :
Exogenous
S100A12 increased the production of MMP-13 and
VEGF in human OA chondrocytes
Tuo et al., J Recept Signal Transduct Res 2013
:
The
upregulation of calcitonin receptor-like receptor (CRLR), FAK,
VEGF and its two main receptors ( FLT1, KDR ) by
CGRP was also more pronounced than that obtained by VEGF165