Takeda et al., Genes Dev 2006
(Cell Transformation, Neoplastic) :
We show that MLL and MLL2 directly target E2Fs for Cyclin expression
Ansari et al., Br J Cancer 2012
:
The MLL4 regulates expression of various critical cell-cycle regulatory genes such as cyclin D, cyclin E, p27, HOXA5 and HOXB7 via histone H3K4 trimethylation and recruitment of RNA polymerase II