Berlato et al., J Immunol 2002
(MAP Kinase Signaling System) :
Constitutive SOCS-3 expression also down-regulated the mRNA expression of inducible NO synthase and IL-6 and impaired the production of TNF-alpha, mainly at a post-transcriptional level
Qasimi et al., J Biol Chem 2006
:
SOCS3 was essential for IL-10 inhibition of LPS stimulated production of iNOS ( inducible nitric-oxide synthase ) protein and nitric oxide ( NO )