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INS — KCNH4

Text-mined interactions from Literome

Nystrom et al., Mol Endocrinol 1999 : Interestingly, overexpression of Cav-WT in Cos-7 cells significantly enhanced insulin stimulated phosphorylation of Elk-1 ( a mitogen activated protein kinase dependent pathway ) while overexpression of Cav-Mut was without effect
Goetze et al., J Cardiovasc Pharmacol 2000 : TRO at 1-20 microM potently inhibited insulin stimulated , ERK1/2 dependent Elk-1 transcription factor activity
Chen et al., Endocrinology 1998 : In contrast, we did demonstrate that overexpression of alpha2-HSG in adipose cells inhibits both basal and insulin stimulated phosphorylation of Elk-1 ( a transcription factor phosphorylated and activated by mitogen activated protein kinase and other related upstream kinases ) ... We conclude that alpha2-HSG inhibits insulin stimulated Elk-1 phosphorylation, but not glucose transport, in adipose cells by a mechanism that may involve effector molecules downstream of insulin receptor substrate proteins