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JAG1 — WNT4

Text-mined interactions from Literome

Katoh et al., Int J Mol Med 2007 : Canonical WNT signaling to intestinal progenitor cells leads to transcriptional activation of the JAG1 gene, encoding Serrate-type Notch ligand
Katoh et al., Cancer Biol Ther 2007 (Helicobacter Infections...) : WNT-beta-catenin-TCF/LEF signaling induces upregulation of MYC, CCND1, WISP1, FGF20, JAG1 and DKK1 genes ... WNT-beta-catenin-TCF/LEF signaling induces upregulation of MYC, CCND1, WISP1, FGF20, JAG1 and DKK1 genes
Chen et al., Oncotarget 2010 (Carcinoma...) : We also found that inhibition of Wnt/ß-catenin signaling reduced Jagged1 expression, and co-administration of shRNAs targeting both Notch3 and ß-catenin reduced Jagged1 expression much more than targeting either individual gene ... In addition, Wnt/ß-catenin pathway activation also up-regulated Jagged1
Wang et al., PloS one 2013 : qPCR and RNA in situ hybridization assays reveal that endocardial Jagged1-Notch1 signaling regulates Wnt4 expression in the atrioventricular canal ( AVC ) endocardium and Bmp2 in the AVC myocardium ... These results demonstrate that Jagged1-Notch1 signaling in endocardial cells induces the expression of Wnt4 , which subsequently acts as a paracrine factor to upregulate Bmp2 expression in the adjacent AVC myocardium to signal EMT