◀ Back to GSK3B

GSK3B — MAP2K1

Text-mined interactions from Literome

Takahashi-Yanaga et al., Biochem Biophys Res Commun 2004 : U0126, a MEK1/2 inhibitor, inhibited tyrosine phosphorylation of GSK-3beta, suggesting that MEK1/2 was involved in the phosphorylation of Tyr ( 216 ) in GSK-3beta
Wang et al., Neoplasia (New York, N.Y.) 2006 (Colonic Neoplasms) : The effect of NT was blocked by inhibitors of protein kinase C ( PKC ), but not by inhibitors of MEK1 or phosphatidylinositol-3 kinase, suggesting a predominant role for PKC in GSK-3beta phosphorylation by NT. Pretreatment with Gö6976 ( which inhibits PKCalpha and PKCbeta1 ) or downregulation of endogenous PKCalpha or PKCbeta1 blocked NT-mediated GSK-3beta ( but not GSK-3alpha ) phosphorylation