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IL8 — PRKACB
Text-mined interactions from Literome
Zhang et al., J Immunol 1992
:
In contrast, induction of IL-8 by RA was inhibited by both 1- ( 5-isoquinoline sulfonamide and N- ( 2-gamidinoethyl ) -5-isoquinoline sulfonamide, suggesting the
participation of
PKA in the induction of
IL-8 by RA ... However, activation of
PKA by addition of cAMP analogues was not
sufficient to induce
IL-8 expression
Grandjean-Laquerriere et al., Cytokine 2005
:
In this study, we use specific inhibitors to investigate the
role of both
PKA- and PKC mediated pathways in the regulation of UVB induced
IL-8 expression in NCTC 2544 cell line ... Finally, we concluded that a cAMP independent
PKA activation and a PKC associated pathway are probably
involved in the regulation of UVB induced
IL-8 synthesis in human keratinocytes
Hirano et al., Eur J Pharmacol 2007
:
The synergistic production of MCP-1 and
IL-8 by PGD2 was mimicked by dibutyryl cAMP ( db-cAMP ) and was
inhibited by a
protein kinase A (PKA) inhibitor
Simeone et al., Int J Oncol 2007
(Breast Neoplasms...) :
Protein kinase A (PKA) and protein kinase C ( PKC ) are activated by COX-2 and are
involved in
IL-8 regulation ... Activation of PKC, not
PKA ,
increased IL-8 production and invasion in MCF-7 cells
Gross et al., Gastroenterology 1995
:
The aim of this study was to improve the understanding of the regulation of IL-8 synthesis by investigating the
roles of protein kinase C ( PKC ),
protein kinase A (PKA) , and protein tyrosine kinase ( PTK ) in the induction of
IL-8
Beales et al., Cytokine 1997
:
The aim of this study was to investigate the
roles of
protein kinase A (PKA) , protein kinase C ( PKC ), protein tyrosine kinase ( PTK ) and intracellular calcium in the induction of
IL-8 production by gastric epithelial cells ... Stimulation of
PKA with forskolin or dibutyryl cyclic adenosine monophosphate or inhibition with H89
had no effect on
IL-8 production
Ding et al., Biochem Biophys Res Commun 1997
:
It is concluded that HP and its toxin can increase IL-8 expression in endothelial cells, and the expression of
IL-8 elicited by HP toxin, TNF-alpha, and LPS is partially
dependent on PTK but not
PKA or PKC activation
Jaspers et al., J Cell Physiol 1998
(Adenocarcinoma, Bronchiolo-Alveolar...) :
Exposure to ozone increased
interleukin 8 expression and transcription factor activities in a protein tyrosine kinase ( PTK ) -dependent and
protein kinase A (PKA) dependent , yet protein kinase C ( PKC ) -independent, manner