Gene interactions and pathways from curated databases and text-mining

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FCGR1A — IL4

Text-mined interactions from Literome

van Roon et al., Arthritis Rheum 2003 (Arthritis, Rheumatoid) : Consistent with these effects on SF macrophages, CD64-RiA also inhibited TNFalpha production, interleukin-1beta production, and cartilage degrading activity of RA synovial tissue explants
te Velde et al., J Immunol 1992 : IL-4 induces MHC class II Ag expression but reduces Fc gamma RI expression
Lehmann et al., J Immunol 1994 : In mouse peritoneal macrophages, IL-4 and IL-10 influenced both basal and IFN-gamma induced expression of Fc gamma RI in opposite ways : IL-10 was stimulatory and IL-4 repressed Fc gamma RI expression