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MAP2K1 — SP1

Text-mined interactions from Literome

Chupreta et al., Am J Physiol Cell Physiol 2000 : The results revealed that Sp1 kinase activity ( like gastrin promoter activation ) is inhibited by PD-98059 and, therefore, is dependent on mitogen activated protein kinase kinase 1 ( Mek 1 ) ... Therefore, most EGF stimulated Sp1 kinase activity is Mek 1 dependent and distinct from Erk
Pan et al., J Biol Chem 2002 : Third, overexpression of constitutively active MEK1 stimulates Sp1 phosphorylation and MMP-2 promoter activity and antagonizes the inhibition of NSAIDs