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IL1R1 — MAP3K7

Pathways - manually collected, often from reviews:

• BioCarta nf-kb signaling pathway: IL-1/IL-1R/MYD88/IRAK/TRAF6 complex (IL1A-IL1R1-MYD88-IRAK1-TRAF6) → TAB1/TAK1 complex (MAP3K7IP1-MAP3K7) (modification, activates)
  

Text-mined interactions from Literome

Fraczek et al., J Biol Chem 2008 : The kinase activity of IL-1 receptor associated kinase 4 is required for interleukin-1 receptor/toll-like receptor induced TAK1 dependent NFkappaB activation
Lee et al., Biochim Biophys Acta 2009 : DSCR1-1S also stimulated IL-1R mediated signaling pathways, TAK1 activation , NF-kappaB transactivation, and IL-8 production, all downstream consequences of IL-1R activation