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MIF — MMP13

Text-mined interactions from Literome

Onodera et al., J Biol Chem 2002 : Similarly, a selective mitogen activated protein kinase ( MAPK ) kinase ( MEK)1/2 inhibitor ( PD98059 ) and c-jun/activator protein (AP)-1 inhibitor ( curcumin ) suppressed MMP-13 mRNA up-regulation induced by MIF ... Taken together, these results suggest that MIF increases the MMP-13 mRNA level of rat osteoblasts via the Src related tyrosine kinase-, Ras-, ERK1/2-, and AP-1 dependent pathway
Burger-Kentischer et al., Atherosclerosis 2006 (Aortitis...) : Importantly, the local aortic expression of ICAM-1, MMP-2 , TNF, IL-12, and CD40L was reduced by MIF blockade, as were the levels of the phospho-c-Jun and C/EBPbeta transcription factors
Pakozdi et al., Arthritis Res Ther 2006 (Arthritis, Experimental...) : In the present study, we determined the role of MIF in RA synovial fibroblast MMP production and the underlying signaling mechanisms
Assunção-Miranda et al., J Med Virol 2010 (Alphavirus Infections...) : The use of different strategies to block MIF action, including an anti-MIF antibody, the MIF inhibitor ISO-1 and knockout mice for the MIF gene, showed that cytokine secretion and MMP expression during infection were regulated by MIF , suggesting that this cytokine acts in autocrine and paracrine manner upstream in the macrophage activation cascade