Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Elstad et al., J Immunol 1994 : Ligation of CD11b/CD18 was not sufficient for PAF synthesis suggesting that an additional receptor was involved
Kim et al., Surgery 1994 : We have previously shown that platelet activating factor (PAF) primes polymorphonuclear neutrophils ( PMNs ) for superoxide generation and, concurrently, increases CD11/CD18 receptor expression ; both events appear central to the pathogenesis of postinjury multiple organ failure ... PAF also enhanced CD18 expression ( 6.1 +/- 1.1 mean fluorescence intensity versus 10.3 +/- 2.3 ), but beta-adrenoreceptor stimulation ( 10.1 +/- 2.1 ) and AC activation ( 9.7 +/- 1.9 ) had no discernible effect
Knight et al., J Leukoc Biol 1997 : PAF up-regulated the expression of CDllb/CD18 , down-regulated L-selectin, and also increased F-actin assembly in eosinophils
Yoshikawa et al., Biofactors 1998 : PAF induced upregulation of CD11b and CD18 on neutrophils and IL-1 beta increased surface expression of ICAM-1 and VCAM-1 on HUVEC ... Coincubation of neutrophils with alpha-Toc and pretreatment of HUVEC with alpha-Toc significantly reduced PAF induced CD11b/CD18 expression and IL-1 beta induced upregulation of ICAM-1 and VCAM-1, respectively