Gene interactions and pathways from curated databases and text-mining

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MAP2K1 — RNF19A

Text-mined interactions from Literome

Cong et al., Proc Natl Acad Sci U S A 1999 (MAP Kinase Signaling System) : c-Abl induced p38 activation was primarily mediated by mitogen activated protein kinase kinase ( MKK ) 6
Westermarck et al., Mol Cell Biol 2001 (MAP Kinase Signaling System) : Furthermore, arsenite prevented phorbol ester induced phosphorylation of ERK1,2 kinase-MEK1,2 , and this effect was dependent on p38 mediated activation of protein phosphatase 1 (PP1) and PP2A
Edlund et al., Mol Biol Cell 2003 (Prostatic Neoplasms) : Transforming growth factor-beta1 ( TGF-beta ) -induced apoptosis of prostate cancer cells involves Smad7 dependent activation of p38 by TGF-beta activated kinase 1 and mitogen activated protein kinase kinase 3
Reunanen et al., J Biol Chem 1998 : In addition, ceramide dependent induction of MMP-1 expression is potently prevented by PD 98059, a selective inhibitor of MEK1 activation, and by specific p38 inhibitor SB 203580