Gene interactions and pathways from curated databases and text-mining

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MAP2K1 — PTAFR

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: MAP2K1 → PTAFR (increases, PTAFR Activity, MAP2K1 Activity) Axelrad et al., FASEB J 2004*
    Evidence: In human colon carcinoma cells, exogenous addition of PAF inhibited proliferation while concomitantly activating Erk, Mek, and Jun N-terminal kinases