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PLAT — RHO

Text-mined interactions from Literome

Wang et al., Stroke 2006 (Cerebral Hemorrhage...) : This effect may be mediated via the Rho kinase pathway because tPA induced activation of Rho signaling was suppressed by simvastatin, and tPA induced MMP-9 levels were similarly reduced by the Rho kinase inhibitor Y-27632 ( 1 to 10 micromol/L )
Aarons et al., Ann Surg 2007 (Disease Models, Animal...) : The effect of a Rho protein inhibitor, exoenzyme C3 transferase, on tPA production was also determined ... The Rho protein inhibitor increased tPA production and rescued tPA production from the inhibitory effect of GGPP