Radoja et al., Mol Cell Biol 2000
(Skin Diseases) :
We conclude that GR suppresses keratin gene expression through two independent mechanisms : directly, through interactions of keratin nGREs with four GR monomers, as well as indirectly, by blocking the AP1 induction of keratin gene expression
Karimipour et al., Arch Dermatol 2009
:
Coarse-grit microdermabrasion induces a wound healing response characterized by rapid increase in induction of cytokeratin 16 and activation of the AP-1 transcription factor in the epidermis