Gene interactions and pathways from curated databases and text-mining

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NOX1 — TPR

Text-mined interactions from Literome

Zhang et al., Arterioscler Thromb Vasc Biol 2011 : We conclude that TPr activation via PKC-? mediated NAD ( P ) H oxidase activation increases both O ( 2 ) ( ·- ) and ONOO ( - ), resulting in eNOS uncoupling in endothelial cells
Bayat et al., Free Radic Biol Med 2012 : In conclusion, activation of TPr enhances IL-1ß induced Nox1 expression in VSMCs, which is responsible for the up-regulation of monocyte adhesion