Gene interactions and pathways from curated databases and text-mining

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GNA13 — SRF

Text-mined interactions from Literome

Lin et al., J Biol Chem 2002 : Transfection of GTPase-deficient Galpha subunits ( GalphaQL ; constitutively active form ) demonstrated that SRF was activated by Galpha(13)QL but only marginally by Galpha ( q ) QL and Galpha(12)QL in Jurkat cells
Suzuki et al., Proc Natl Acad Sci U S A 2003 : LARG synergistically stimulated SRF activation by Galpha12 and Galpha13 in HeLa cells, and the SRF activation by Galpha12-LARG was further stimulated by coexpression of Tec tyrosine kinase
Nakamura et al., Mol Pharmacol 2004 (Leukemia) : Compared with wild-type Galpha13, Galpha13K204A induced much less serum-response factor activation when expressed in HeLa cells