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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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HTR1A — MAPK15

Text-mined interactions from Literome

Chen et al., Eur J Pharmacol 2002 : 5-HT1A receptor mediated regulation of mitogen activated protein kinase phosphorylation in rat brain
Kushwaha et al., Eur J Neurosci 2005 : In undifferentiated RN46A cells stably transfected with the wild-type 5-HT1A receptor, 5-HT1A receptor activation inhibited forskolin induced cyclic adenosine monophosphate ( cAMP ) formation ( by 50 % ), increased [Ca2+ ] i, and induced a novel inhibition ( up to 60 % ) of phospho-p42/p44-mitogen activated protein kinase ( MAPK )
Garnovskaya et al., Biochemistry 1996 : Ras dependent activation of fibroblast mitogen activated protein kinase by 5-HT1A receptor via a G protein beta gamma-subunit initiated pathway ... These data demonstrate that the 5-HT1A receptor mediates MAPK activity by convergence upon a common activation pathway that is shared with receptor tyrosine kinases
Garnovskaya et al., J Biol Chem 1997 : Acceleration of proton efflux was not inhibited by sequestration of G protein betagamma-subunits, a maneuver that blocked 5-HT1A receptor activation of mitogen activated protein kinase