Lee et al., J Biochem Mol Biol 2002
:
The AP1 activation by TRAF2, TRAF5 , and TRAF6 was also greatly suppressed by the dominant negative TAK1
Xu et al., J Biol Chem 2004
:
TRAF7 specifically interacted with MEKK3 and potentiated MEKK3 mediated AP1 and CHOP activation ... Depletion of TRAF7 by antisense RNA inhibited MEKK3 mediated AP1 and CHOP activation ... Domain mapping experiments indicated that TRAF7 potentiated MEKK3 mediated AP1 and CHOP activation and induced apoptosis through distinct domains
Blackwell et al., Mol Cell Biol 2009
(Lymphoma) :
Notably, TRAF2 phosphorylation increased both basal and inducible c-Jun and NF-kappaB activities and rendered cells resistant to stress induced apoptosis
Scudiero et al., J Biol Chem 2012
:
Tumor necrosis factor (TNF) receptor associated factor 7 is required for TNFa induced Jun NH2-terminal kinase activation and promotes cell death by regulating polyubiquitination and lysosomal degradation of c-FLIP protein