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APOB — PLTP

Text-mined interactions from Literome

Jiang et al., Nat Med 2001 (Arteriosclerosis...) : In ApoB-transgenic and ApoE-deficient backgrounds, PLTP deficiency resulted in reduced production and levels of BLp and markedly decreased atherosclerosis
Lie et al., J Lipid Res 2004 (Arteriosclerosis...) : PLTP expression caused a strong PLTP dose dependent decrease in VLDL and LDL cholesterol ( -26 % and -69 % ) and a decrease in HDL cholesterol ( -70 % )
Jiang et al., J Biol Chem 2005 (Vitamin E Deficiency) : Phospholipid transfer protein deficiency impairs apolipoprotein-B secretion from hepatocytes by stimulating a proteolytic pathway through a relative deficiency of vitamin E and an increase in intracellular oxidants
Jiang et al., Curr Opin Lipidol 2006 (Atherosclerosis...) : In apolipoprotein B transgenic mice, phospholipid transfer protein deficiency enhances reactive oxygen species dependent degradation of newly synthesized apolipoprotein B via a post-endoplasmic reticulum process, as well as improving the antiinflammatory properties of HDL in mice
Luo et al., J Pharmacol Exp Ther 2010 : Pharmacologic inhibition of phospholipid transfer protein activity reduces apolipoprotein-B secretion from hepatocytes